Posted by email@example.com - Posted on 04/18/2016 00:02:16 Glaucoma
The most common corneal abnormaility associated with this condition is what ?
Diagnosis: Axenfeld-Rieger syndrome
The most common corneal abnormality associated with A-R syndrome is Posterior embryotoxon (prominent and anteriorly displaced Schwalbe line)
Autosomal Dominant disorder
Adnormal development of neural crest cells leading to abnormal development of anterior chamber angle, iris and trabecular meshwork.
50% develop glaucoma
A-R syndrome systemic associations: defects of teeth, maxillary hypoplasia, redundant periumbical skin, pituitary abnormalities, hypospadias.
Peters anamoly: corneal opacity with iris adhesions to central cornea. Usually sporadic. 50% develop glaucoma; Assc with central defect in corneal endothelium and descemet's membrane..
ICE or Iridocorneal endothelial syndrome: Unilateral condition, 20-40 year old women,, abnormal corneal endothelium is basic pathology; High PAS with elevated IOP; Iris atrophy with holes; Glaucoma in 50%;